Highly selective catalysts for the hydrogenation of alkynols: A review

The semi-hydrogenation of alkynols to enols is a crucial process in the production pharmaceuticals, agrochemicals, fragrances, and flavors that involves complex set parallel consecutive isomerization hydrogenation reactions proceeds via several key intermediates. In view industrial importance large-scale enol through alkynol hydrogenation, various noble non-noble metal (e.g., Ni Pd)-based catalysts promoting this transformation have been developed. This paper reviews design highly selective for alkynols, focusing on role additives, second metals, catalyst supports, reaction conditions combining catalytic kinetics with theoretical calculations establish mechanism decisive factors boosting selectivity. Finally, strategy designing efficient based characteristics aqueous-phase proposed.